The Dangers of Smoking Mushrooms

The Dangers of Smoking Mushrooms

The Dangers of Smoking Mushrooms


Smoking mushrooms, a practice that has gained sporadic attention in certain circles is ineffective in producing the desired effects and poses significant health risks. This guide sheds light on the potential dangers of attempting to smoke mushrooms. It will explore the adverse health effects, including respiratory problems, the formation of toxic byproducts, and the absence of the anticipated psychoactive outcomes. It is essential to understand that consuming mushrooms through smoking is neither safe nor recommended, and individuals should be well-informed about the potential hazards before making any decisions.

Respiratory Issues and Beyond     

Ineffective Inhalation:

Mushrooms primarily comprise chitin, a complex carbohydrate that is challenging to combust. When subjected to high heat, chitin does not break down efficiently, leading to incomplete combustion and the release of toxic byproducts. Smoking mushrooms, therefore, often results in inadequate inhalation of active compounds, rendering the practice ineffective for achieving any psychoactive effects.

Respiratory Irritation:

The act of smoking mushrooms can result in the inhalation of fine particulate matter and irritants. These particles can irritate the delicate lining of the respiratory tract, leading to inflammation, coughing, and potentially exacerbating pre-existing respiratory conditions such as asthma or chronic obstructive pulmonary disease (COPD).

Toxic Byproducts and Health Risks

Toxic Combustion Byproducts:

When subjected to high temperatures during smoking, chitin can produce harmful byproducts such as acetaldehyde and other volatile organic compounds. These compounds are known to have carcinogenic and mutagenic properties, increasing the risk of cellular damage and potentially leading to long-term health problems.

Fungal Contaminants:

Smoking mushrooms also raises concerns about the potential inhalation of fungal contaminants that could be present on the surface of the mushrooms. These contaminants may include mold spores, allergens, or mycotoxins, contributing to respiratory distress, allergies, and other adverse health effects.

Psychoactive Effects and Misconceptions                           

Lack of Psychoactive Effects:

Smoking mushrooms is widely regarded as ineffective in achieving the desired psychoactive effects. The active compounds in mushrooms, primarily psilocybin, and psilocin, require a specific temperature range for proper decarboxylation and activation. With its high temperatures, smoking tends to degrade these compounds, resulting in diminished or negligible psychoactive outcomes.

Misconceptions and Unrealistic Expectations:

The internet and popular culture have perpetuated misconceptions about the potential benefits of smoking mushrooms. It has led to unrealistic expectations among individuals who attempt to smoke them, only to be disappointed by the lack of intended effects. These misconceptions can further contribute to the allure of smoking mushrooms, despite the lack of scientific basis.

Unveiling the Chemistry of Psychedelic Mushrooms

Psychedelic mushrooms, also known as magic mushrooms, have been revered for centuries due to their mind-altering effects. The chemical compounds responsible for these effects are psilocybin and psilocin, which belong to a class of substances called tryptamines. Understanding the intricate chemistry behind these compounds is crucial for comprehending the psychedelic experience and their potential therapeutic applications.

The Active Compounds: Psilocybin and Psilocin

  1. Psilocybin:

After ingestion, it is a prodrug metabolically converted into its active form, psilocin. Psilocybin is a tryptamine alkaloid that shares a molecular structure with serotonin, an important neurotransmitter for controlling mood and cognition.


Psilocin is the active metabolite of psilocybin, responsible for producing the psychedelic effects experienced by users. Like psilocybin, psilocin is also a tryptamine alkaloid and acts as a partial agonist at serotonin receptors in the brain. Its chemical structure is similar to serotonin, allowing it to interact with these receptors and induce altered states of consciousness.

Chemical Structure and Receptor Interaction

Tryptamine Backbone:

Both psilocybin and psilocin share a common tryptamine backbone consisting of a bicyclic indole ring. This structural feature allows these compounds to interact with specific serotonin receptors, particularly the 5-HT2A receptor, which is known to be involved in the psychedelic effects.

Serotonin Receptor Affinity:

Psilocybin and psilocin exhibit high affinity for certain serotonin receptor subtypes, primarily the 5-HT2A receptor. Upon binding to these receptors, they initiate a cascade of neural activity, leading to alterations in sensory perception, emotions, and cognition, characteristic of the psychedelic experience.

Metabolism and Processing in the Body  

Oral Ingestion:

The most common method of consuming psychedelic mushrooms is through oral ingestion. When ingested, psilocybin is rapidly absorbed from the gastrointestinal tract and enters the bloodstream.

Metabolism into Psilocin:

In the liver, psilocybin undergoes enzymatic dephosphorylation, converting it into psilocin. This conversion is a crucial step for the psychoactive effects to manifest, as psilocin is the compound that directly interacts with serotonin receptors in the brain.

Blood-Brain Barrier:

Once psilocin is formed, it readily crosses the blood-brain barrier due to its structural similarity to serotonin. It enables psilocin to access various brain regions and interact with serotonin receptors, leading to altered perceptions and consciousness.

Serotonin Receptor Activation:

As psilocin binds to serotonin receptors, particularly the 5-HT2A receptor, it triggers a cascade of signaling events that modulate neural activity. This increased neural activity leads to sensory processing, mood, and cognition changes, resulting in the characteristic psychedelic experience.

Duration and Elimination:

The duration of the psychedelic experience varies based on factors such as dosage, individual metabolism, and mushroom species. After the effects wear off, psilocin is metabolized in the liver and excreted via urine.

Therapeutic Potential and Ongoing Research

Psychedelic Therapy:

The therapeutic potential of psilocybin and psilocin has gained significant attention recently. Studies have shown promising results in psychedelic-assisted therapy for depression, anxiety, and PTSD.

Neuroplasticity and Brain Connectivity:

Psychedelics have been found to increase neuroplasticity and promote new patterns of brain connectivity. It may underlie their potential to facilitate long-term changes in psychological well-being.

Exploring Safe Methods of Consuming Psychedelic Mushrooms

Psychedelic mushrooms have a rich history of traditional use and contemporary exploration, and understanding safe and established consumption methods is essential for those seeking to embark on a transformative journey. This guide delves into two widely practiced methods of consuming psychedelic mushrooms: oral ingestion (eating) and brewing them into tea. By exploring these methods, their effects, and precautions, individuals can make informed decisions and minimize potential risks while maximizing the benefits of their psychedelic experiences.

Oral Ingestion of Psychedelic Mushrooms

The Basics:

Oral ingestion is perhaps the most straightforward and traditional method of consuming psychedelic mushrooms. Dried mushrooms are typically ingested whole or crushed into a powder and then consumed orally.

Dosage Considerations:

The dosage of psychedelic mushrooms varies depending on factors such as the individual’s body weight, tolerance, and the desired intensity of the experience.

Onset and Duration:

After ingestion, the effects usually manifest within 20 to 60 minutes and peak around 2 to 3 hours. The overall duration of the experience can last between 4 to 6 hours or longer.


Oral ingestion of psychedelic mushrooms results in a gradual onset of effects, allowing individuals to ease into the experience. Users may undergo shifts in sensory perception, altered thought patterns, and emotional introspection.


It’s essential to create a comfortable and safe environment, especially during the peak of the experience. Having a trusted trip sitter, staying hydrated, and avoiding interactions with other substances are critical precautions.

Brewing Psychedelic Mushroom Tea

The Tea-Making Process:

Mushroom tea involves boiling or steeping dried mushrooms in hot water to extract the active compounds, psilocybin, and psilocin.

Dosage and Potency:

Brewing tea can alter the potency and onset of effects compared to oral ingestion. The effects may occur more rapidly and intensely due to the faster absorption of the compounds in the digestive system.

Onset and Duration:

The effects of mushroom tea typically start to be felt within 15 to 30 minutes and peak around 1 to 2 hours. The overall duration of the experience remains similar to oral ingestion.


Mushroom tea offers a more rapid onset, potentially leading to a more intense experience. Users may also report reduced nausea compared to consuming dried mushrooms.


Similar precautions as with oral ingestion apply to mushroom tea. Additionally, users should be cautious about the dosage, as the effects can be stronger and more abrupt.

Comparing the Methods

Personal Preferences:

Choosing between oral ingestion and mushroom tea often comes down to personal preferences. Some individuals may appreciate the gradual onset and extended experience of oral ingestion, while others may prefer the faster onset and potentially reduced nausea of mushroom tea.

Duration and Intensity:

Oral ingestion typically leads to a longer and smoother experience, while mushroom tea can produce a more intense and rapid onset of effects.

Nausea Considerations:

Mushroom tea may reduce the likelihood of nausea, making it a preferred option for individuals sensitive to stomach discomfort.


In conclusion, smoking mushrooms is ineffective in producing psychoactive effects and poses substantial risks to respiratory health and overall well-being. The complexities of mushroom composition, the formation of toxic byproducts, and the lack of decarboxylation required for activating the active compounds all contribute to this practice’s ineffectiveness and potential hazards. It is vital for individuals to be well-informed about these dangers and to consider safer and more established methods of consuming mushrooms, such as oral ingestion or brewing into tea, to minimize risks and optimize potential benefits.

Before embarking on a psychedelic journey, individuals should research extensively, seek guidance from experienced individuals or professionals, and be aware of the legal status of psychedelic substances in their jurisdiction. By approaching these experiences with respect, mindfulness, and preparation, individuals can unlock the potential for personal growth, introspection, and transformation that psychedelic mushrooms may offer.

Dr Saba Shahzad

I am Dr. Saba Shahzad, a medical student, and writer. My background in the medical field has given me a deep understanding of the latest research and trends, which I can translate into clear and easy-to-understand language for a lay audience. As a medical student, I am constantly learning new information and expanding my knowledge in the field, which I can apply to my work as a medical writer. Alongside my passion for the medical field, I also have a hobby of writing, specifically creative fiction. I spend my free time exploring new genres and honing my craft, and I have had work published in various literary magazines and online publications. My writing hobby complements my career as a medical writer, as it allows me to think creatively and approach problems from different angles. I am also a dedicated and hardworking individual who desires to excel in everything I do. With my combination of medical expertise, writing talent, and want to excel, I can provide valuable and accurate medical communication for any team in need. My medical and writing skills would be an asset to any organization.

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